ARTICLE UPDATE - How does negative emotion cause false memories?

Brainerd CJ, Stein LM, Silveira RA, Rohenkohl G, Reyna VF.

Psychological Science, 19, 919-925

Remembering negative events can stimulate high levels of false memory, relative to remembering neutral events. In experiments in which the emotional valence of encoded materials was manipulated with their arousal levels controlled, valence produced a continuum of memory falsification. Falsification was highest for negative materials, intermediate for neutral materials, and lowest for positive materials. Conjoint-recognition analysis produced a simple process-level explanation: As one progresses from positive to neutral to negative valence, false memory increases because (a) the perceived meaning resemblance between false and true items increases and (b) subjects are less able to use verbatim memories of true items to suppress errors.

ARTICLE UPDATE - Chronometric features of processing unpleasant stimuli: a functional MRI-based transcranial magnetic stimulation study.

Kaffenberger T, Baumgartner T, Koeneke S, Jäncke L, Herwig U.

Neuroreport, 19, 777-781

The quick identification of potentially threatening events is a crucial cognitive capacity to survive in a changing environment. Previous functional MRI data revealed the right dorsolateral prefrontal cortex and the region of the left intraparietal sulcus (IPS) to be involved in the perception of emotionally negative stimuli. For assessing chronometric aspects of emotion processing, we applied transcranial magnetic stimulation above these areas at different times after negative and neutral picture presentation. An interference with emotion processing was found with transcranial magnetic stimulation above the dorsolateral prefrontal cortex 200-300 ms and above the left intraparietal sulcus 240/260 ms after negative stimuli. The data suggest a parallel and conjoint involvement of prefrontal and parietal areas for the identification of emotionally negative stimuli.

ARTICLE UPDATE - Affective flexibility: evaluative processing goals shape amygdala activity.

Cunningham WA, Van Bavel JJ, Johnsen IR.

Psychological Science, 19, 152-160

Although early research implicated the amygdala in automatic processing of negative information, more recent research suggests that it plays a more general role in processing the motivational relevance of various stimuli, suggesting that the relation between valence and amygdala activation may depend on contextual goals. This study provides experimental evidence that the relation between valence and amygdala activity is dynamically modulated by evaluative goals. During functional magnetic resonance imaging, participants evaluated the positive, negative, or overall (positive plus negative) aspects of famous people. When participants were providing overall evaluations, both positive and negative names were associated with amygdala activation. When they were evaluating positivity, positive names were associated with amygdala activity, and when they were evaluating negativity, negative names were associated with amygdala activity. Evidence for a negativity bias was found; modulation was more pronounced for positive than for negative information. These data suggest that the amygdala flexibly processes motivationally relevant evaluative information in accordance with current processing goals, but processes negative information less flexibly than positive information.

ARTICLE UPDATE - Emotional influences on spatial attention.

Foster PS, Drago V, Webster DG, Harrison DW, Crucian GP, Heilman KM.

Neuropsychology, 22, 127-135

The relationships between the anterior-posterior and left-right regions of the brain have been characterized as mutually inhibitory. Whereas the left hemisphere attends to right proximal hemispace and is associated with positive emotions, the right hemisphere attends to left distal hemispace and is associated with negative emotions. Because of the excitatory and inhibitory influences between the left and right frontal and posterior regions of the brain, the expression of emotion will result in an ipsilateral attentional bias. Given these functional systems, we hypothesized that positive emotions would be associated with a bias for left distal hemispace and negative emotions would be associated with a bias for right proximal hemispace. We tested these hypotheses by having 138 undergraduate students place emotionally labeled pegs on a large board. Our results indicated that the positively labeled pegs were placed in left distal hemispace and the relative placement of negatively labeled pegs was rightward and proximally. Whereas numerous research investigations have examined how attention is biased for emotional stimuli, ours is the first investigation to provide evidence that emotions can bias attentional allocation.

ARTICLE UDPATE - How Negative Emotion Enhances the Visual Specificity of a Memory

Elizabeth A. Kensinger, Rachel J. Garoff-Eaton and Daniel L. Schacter

Journal of Cognitive Neuroscience, 19, 1872-1887

Some studies have suggested that emotion primarily increases memory for "gist," and does not enhance memory for detail. There are, however, some instances in which negative objects (e.g., snake, grenade) are remembered with more visual detail than neutral objects (e.g., barometer, blender). In the present functional magnetic resonance imaging (fMRI) study, we examined the encoding processes that lead a person to remember the exact visual details of negative and neutral objects, and to remember which of two decisions were made about the objects (a size decision or an animacy decision). The enhancement in memory for a negative item's visual details appeared to result from enhanced visual processing: The right fusiform gyrus, a region known to be critical for processing exemplar-specific details, showed a greater extent and magnitude of activity during the successful encoding of negative objects. Activity in the right amygdala also corresponded with memory for visual detail, although it did not relate to memory for the task performed with the item. These data provide strong evidence that engagement of some amygdalar regions can correspond with enhanced memory for certain types of details, but does not ensure successful encoding of all contextual details.

ARTICLE UPDATE - The Neural Bases of Emotion Regulation: Reappraisal and Suppression of Negative Emotion.

Goldin PR, McRae K, Ramel W, Gross JJ.

Biological Psychiatry, in press

Background

Emotion regulation strategies are thought to differ in when and how they influence the emotion-generative process. However, no study to date has directly probed the neural bases of two contrasting (e.g., cognitive versus behavioral) emotion regulation strategies. This study used functional magnetic resonance imaging (fMRI) to examine cognitive reappraisal (a cognitive strategy thought to have its impact early in the emotion-generative process) and expressive suppression (a behavioral strategy thought to have its impact later in the emotion-generative process).

Methods

Seventeen women viewed 15 sec neutral and negative emotion-eliciting films under four conditions—watch-neutral, watch-negative, reappraise-negative, and suppress-negative—while providing emotion experience ratings and having their facial expressions videotaped.

Results

Reappraisal resulted in early (0–4.5 sec) prefrontal cortex (PFC) responses, decreased negative emotion experience, and decreased amygdala and insular responses. Suppression produced late (10.5–15 sec) PFC responses, decreased negative emotion behavior and experience, but increased amygdala and insular responses.

Conclusions

These findings demonstrate the differential efficacy of reappraisal and suppression on emotional experience, facial behavior, and neural response and highlight intriguing differences in the temporal dynamics of these two emotion regulation strategies.

Key Words: Amygdala; cognitive control; emotion; emotion regulation; fMRI; insula

ARTICLE UPDATE - Things are sounding up: affective influences on auditory tone perception.

Weger UW, Meier BP, Robinson MD, Inhoff AW.

Psychonomic Bulletin & Review, 14, 517-521

Recent studies have documented robust and intriguing associations between affect and performance in cognitive tasks. The present two experiments sought to extend this line of work with reference to potential cross-modal effects. Specifically, the present studies examined whether word evaluations would bias subsequent judgments of low- and high-pitch tones. Because affective metaphors and related associations consistently indicate that positive is high and negative is low, we predicted and found that positive evaluations biased tone judgment in the direction of high-pitch tones, whereas the opposite was true of negative evaluations. Effects were found on accuracy rates, response biases, and reaction times. These effects occurred despite the irrelevance of prime evaluations to the tone judgment task. In addition to clarifying the nature of these cross-modal associations, the present results further the idea that affective evaluations exert large effects on perceptual judgments related to verticality.

ARTICLE UPDATE - Pleasantness bias in flashbulb memories: positive and negative flashbulb memories of the fall of the Berlin Wall among East and West

Bohn A, Berntsen D.

Memory & Cognition, 35, 565-577

Flashbulb memories for the fall of the Berlin Wall were examined among 103 East and West Germans who considered the event as either highly positive or highly negative. The participants in the positive group rated their memories higher on measures of reliving and sensory imagery, whereas their memory for facts was less accurate than that of the participants in the negative group. The participants in the negative group had higher ratings on amount of consequences but had talked less about the event and considered it less central to their personal and national identity than did the participants in the positive group. In both groups, rehearsal and the centrality of the memory to the person's identity and life story correlated positively with memory qualities. The results suggest that positive and negative emotions have different effects on the processing and long-term retention of flashbulb memories.

ARTICLE UPDATE - Gaze fixations predict brain activation during the voluntary regulation of picture-induced negative affect.

Carien M. van Reekuma, Tom Johnstone, Heather L. Urry, Marchell E. Thurow, Hillary S. Schaefer, Andrew L. Alexander and Richard J. Davidson

NeuroImage, in press

Recent studies have identified a distributed network of brain regions thought to support cognitive reappraisal processes underlying emotion regulation in response to affective images, including parieto-temporal regions and lateral/medial regions of prefrontal cortex (PFC). A number of these commonly activated regions are also known to underlie visuospatial attention and oculomotor control, which raises the possibility that people use attentional redeployment rather than, or in addition to, reappraisal as a strategy to regulate emotion. We predicted that a significant portion of the observed variance in brain activation during emotion regulation tasks would be associated with differences in how participants visually scan the images while regulating their emotions. We recorded brain activation using fMRI and quantified patterns of gaze fixation while participants increased or decreased their affective response to a set of affective images. fMRI results replicated previous findings on emotion regulation with regulation differences reflected in regions of PFC and the amygdala. In addition, our gaze fixation data revealed that when regulating, individuals changed their gaze patterns relative to a control condition. Furthermore, this variation in gaze fixation accounted for substantial amounts of variance in brain activation. These data point to the importance of controlling for gaze fixation in studies of emotion regulation that use visual stimuli.

ARTICLE UPDATE - Neural Correlates of Positive and Negative Emotion Regulation

Sang Hee Kim and Stephan Hamann

Journal of Cognitive Neuroscience, 19, 776-798

The ability to cope adaptively with emotional events by volitionally altering one's emotional reactions is important for psychological and physical health as well as social interaction. Cognitive regulation of emotional responses to aversive events engages prefrontal regions that modulate activity in emotion-processing regions such as the amygdala. However, the neural correlates of the regulation of positive emotions remain largely unexplored. We used event-related functional magnetic resonance imaging to examine the neural correlates of cognitively increasing and decreasing emotional reactions to positive and negative stimuli. Participants viewed negative, positive, and neutral pictures while attempting to increase, decrease, or not alter their emotional reactions. Subjective reactions were assessed via on-line ratings. Consistent with previous studies, increasing negative and positive emotion engaged primarily left-lateralized prefrontal regions, whereas decreasing emotion activated bilateral prefrontal regions. Different activations unique to increasing versus decreasing emotion were observed for positive and negative stimuli: Unique increase-related activations were observed only for positive stimuli, whereas unique decrease-related activations were observed only for negative stimuli. Regulation also modulated activity in the amygdala, a key emotion-processing region. Regulation effects on amygdala activity were larger for positive than for negative stimuli, potentially reflecting a greater malleability of positive emotional reactions. Increasing and decreasing positive and negative emotion can thus increase and decrease subjective reactions and associated amygdala activity in line with regulatory goals, and is associated with different patterns of prefrontal activation as a function of emotional valence and regulatory goal.

ARTICLE UPDATE - Amygdala reactivity predicts automatic negative evaluations for facial emotions.

Dannlowski U, Ohrmann P, Bauer J, Kugel H, Arolt V, Heindel W, Suslow T.

Psychiatry Research, in press

The amygdala is a key structure in a limbic circuit involved in the rapid and unconscious processing of facial emotions. In the present study, the role of the amygdala in automatic, involuntary appraisal processes, which are believed to be a crucial component of emotion processing, was investigated in 23 healthy subjects. Amygdala activity was recorded in response to masked displays of angry, sad, and happy facial expressions using functional magnetic resonance imaging (fMRI). In a subsequent experiment, the subjects performed a masked affective priming task that characterizes automatic emotion processing by investigating the biasing effect of subliminally presented emotional faces on evaluative ratings to subsequently presented neutral stimuli. In the affective priming task, significant valence-congruent evaluation manipulation was observed. Subjects rated neutral targets more positively if they were primed by happy faces. Significant correlations were found between amygdala responses to masked negative facial expressions and negative evaluation shifts elicited by the corresponding emotion quality in the affective priming task. Spontaneous amygdala reactivity to facial emotions appears to be a determinant of automatic negative evaluative response tendencies. This finding might shed some light on how amygdala hyperresponsivity contributes to negative cognitive biases commonly observed in affective disorders.